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Best Med Spas in Murrells Inlet, SC

Murrells Inlet built its name on seafood, marsh views, and a slower pace than its famous neighbor to the north, and its med spa market follows that temperament. This page lists 20 providers for the Inlet, and it also covers Surfside Beach, whose residents are a short drive down Highway 17. Most practices line the Business 17 and Bypass corridors near Inlet Square, which keeps parking simple and errands easy to combine.

Grand Strand Health and Wellness on the Highway 17 Bypass is the largest operation among the top listings, rated 4.8 stars from 554 reviews and combining med spa services with massage, chiropractic care, and physical therapy. DermaVogue on Business 17 earns 4.9 stars from 201 reviews and lists weight loss services alongside its day spa format. Jolie Visage Rejuvenation Centre in Inlet Square Drive holds a perfect 5 stars from 193 reviews, mixing esthetics with health spa and weight loss offerings.

Rejuva Med Spa, located at The Courtyard, also scores a perfect 5 from 179 reviewers, and Pure Aesthetics on Inlet Square Drive matches that perfect rating across 136 reviews. A striking pattern emerges from those numbers: several Inlet practices hold flawless ratings on meaningful review counts, which in a small, word-of-mouth community usually reflects consistent personal service rather than marketing muscle. The treatment landscape leans toward facials, skin care, weight management support, and wellness services, with injectables available through the medically supervised practices.

Retirees form a large share of the local clientele, so expect unhurried appointments and providers who explain options plainly. Seasonal visitors swell the MarshWalk area in summer, yet the med spas serve locals year-round and rarely feel rushed outside holiday weeks. Compare practices by asking about the supervising physician, the injector's experience, and what follow-up is included after a first treatment.

Weekday mornings along the Inlet are usually the calmest time to visit, before lunch crowds and MarshWalk traffic build.

Ranked: 20 med spas in Murrells Inlet

Ordered by Google rating × review count. Evidence beside every name.

1

Grand Strand Health And Wellness

★★★★★ 4.8 (554 Google reviews)
4717 US Highway 17 Bypass South, Murrells Inlet, SC 29576
Medical spa; Massage therapist; Chiropractor; Physical therapy clinic
2

DermaVogue

★★★★★ 4.9 (201 Google reviews)
2347 US-17 BUS, Murrells Inlet, SC 29576
Medical spa; Day spa; Spa; Weight loss service
3

Jolie Visage Rejuvenation Centre

★★★★★ 5 (193 Google reviews)
804 Inlet Square Dr D, Murrells Inlet, SC 29576
Medical spa; Esthetics service; Health spa; Weight loss service
4

Rejuva Med Spa

★★★★★ 5 (179 Google reviews)
The Courtyard, 1500 US-17 BUS, Ste 307, Surfside Beach, SC 29575
Medical spa
5

Pure Aesthetics

★★★★★ 5 (136 Google reviews)
870 Inlet Square Dr, Murrells Inlet, SC 29576
Medical spa
6

Posh Aesthetics and Salon

★★★★★ 4.9 (103 Google reviews)
631 Bellamy Ave, Murrells Inlet, SC 29576
Medical spa; IV therapy service; Permanent make-up clinic; Skin care clinic
7

Massage Care LLC

★★★★★ 4.9 (90 Google reviews)
1010 5th Ave N #104, Surfside Beach, SC 29575
Medical spa; Massage therapist; Sports massage therapist
8

dewySKIN holistic + corrective SPA

★★★★★ 5 (52 Google reviews)
12060 Frontage Rd Apt d, Murrells Inlet, SC 29576
Medical spa; Spa
9

Waccamaw Medical Spa

★★★★☆ 4.5 (48 Google reviews)
3635 Old Kings Hwy, Murrells Inlet, SC 29576
Medical spa; Day spa; Facial spa; Health spa
10

Aqua Vitae - Myrtle Beach, SC - Hormone Therapy & Weight Loss Clinic

★★★★★ 5 (39 Google reviews)
637 Bellamy Ave # A, Murrells Inlet, SC 29576
Medical spa; Medical clinic; Women's health clinic; Weight loss service
11

BraVa Health & MedSpa

★★★★★ 4.6 (28 Google reviews)
4959 US Highway 17 Bypass South, Murrells Inlet, SC 29576
Medical spa
12

Atlantic Med Spa

★★★★★ 5 (18 Google reviews)
4717 US Highway 17 Bypass South 2nd Floor Unit C, Murrells Inlet, SC 29576
Medical spa
13

Pure Serenity Skin

★★★★★ 5 (15 Google reviews)
3334 US-17 BUS, Murrells Inlet, SC 29576
Medical spa
14

Creekside Salon and Spa, Murrells Inlet

★★★★★ 4.9 (14 Google reviews)
5182 Horry Dr Unit B, Murrells Inlet, SC 29576
Medical spa; Health spa; Nail salon; Spa
15

Pawleys Lymphatic Wellness

★★★★★ 5 (11 Google reviews)
3577 US-17 BUS Business Unit C, Murrells Inlet, SC 29576
Medical spa; Massage therapist; Registered general nurse; Wellness center
16

Coastal Facial Rejuvenation and Body Sculpting

★★★★★ 5 (7 Google reviews)
3328 US-17 BUS, Murrells Inlet, SC 29576
Medical spa
17

Dermalaire Medical Spa

★★★★★ 5 (4 Google reviews)
671 Jamestown Dr #202c, Murrells Inlet, SC 29576
Medical spa
18

Inlet Med Spa

4447 US-17 BUS, Murrells Inlet, SC 29576
Medical spa
19

Pure Dermatology by Medicos

4111 Murrells Inlet Rd, Murrells Inlet, SC 29576
Medical spa
20

Smart Lipo MD

4017 Ocean Hwy #2, Murrells Inlet, SC 29576
Medical spa; Plastic surgeon

Murrells Inlet Med Spas FAQ

What does medical weight loss at a med spa involve?
At its best, it is a supervised program rather than a product sale: an intake evaluation, labs where appropriate, a prescription plan managed by a licensed clinician, and regular check-ins on progress and side effects. Several Murrells Inlet practices list weight loss among their services, so ask each one who prescribes, how often you are monitored, and what the maintenance plan looks like after you reach your goal. Programs that skip the medical workup or promise fixed pounds per week deserve skepticism.
I have sensitive skin. What should I tell a Murrells Inlet provider?
Everything, in detail: past reactions to products, rosacea or eczema diagnoses, allergies, and medications including retinoids and antibiotics. Sensitive skin changes which peels, lasers, and active ingredients are safe, and a careful Georgetown County provider will patch-test or start with gentler settings rather than pushing a standard protocol. Bring a list of the products you currently use. If your skin flares after treatment, you want a practice with a clear follow-up path, not one that blames your home routine by default.
How do I choose between neighboring practices in a small community?
In Murrells Inlet, reputation travels by conversation, so use that. Ask friends and neighbors about their actual experiences, then book consultations at your top two choices. Compare who performs the treatment, how thoroughly they assess your skin, whether pricing is itemized in writing, and how follow-up works if you are unhappy. Small practices live on repeat business along the Highway 17 corridor, which generally aligns their incentives with yours, but the consultation is still where you verify that alignment personally.
When should I book treatments before a Murrells Inlet wedding or reunion?
Work backward from the date on the calendar. Begin any laser series or new skincare routine three to six months ahead, because those gains accumulate slowly. Place injectables roughly eight weeks before the event, leaving room for swelling to settle and a touch-up if needed. Reserve the final fortnight for nothing experimental: a gentle facial early in that window is fine, but no first-time filler or strong peel. Inlet practices handle event timelines regularly, so share your date at the first consultation.

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